Pertactin (PRN) is an outer membrane protein expressed by Bordetella pertussis, Bordetella parapertussis, and Bordetella bronchiseptica, which induces protective immunity to Bordetella infections.
The presence of the Bordetella gene fragment is then detected by hybridization to a Bordetella-specific probe.
Two bacteria of the genus Bordetella are responsible for the pertussis syndromes among humans: Bordetella pertussis and Bordetella parapertussis.
Bordetella pertussis specific antibody response
Bordetella pertussis specific antibody response
Isolation of Bordetella pertussis from a clinical specimen
Two bacteria of the genus Bordetella are responsible for the pertussis syndromes among humans: Bordetella pertussis and Bordetella parapertussis.
The attenuated mutated Bordetella strain can be used in an immunogenic composition or a vaccine for the treatment or prevention of a Bordetella infection.
Detection of Bordetella pertussis nucleic acid in a clinical specimen
Disclosed herein are methods and compositions for detecting Bordetella pertussis and Bordetella parapertussis by detecting the presence of the IS481 and IS1001 genomic insertion sequences, respectively.
To provide a method of efficiently separating protective components of Bordetella pertussis.
Two bacteria of the genus Bordetella are responsible for the pertussis syndromes among humans: Bordetella pertussis and Bordetella parapertussis.
The most common bacteria is Bordetella bronchiseptica.
Detection of Bordetella pertussis nucleic acid in a clinical specimen
Although often referred to as Bordetella, tracheobronchitis isn’t caused by the Bordetella bronchiseptica bacteria alone.
The present invention also discloses attenuated Bordetella strains of pathogenic origin, and more particularly genetically modified Bordetella strains, which have been attenuated by disruption or inactivation of the aroQ gene.
Although often referred to as Bordetella, tracheobronchitis isn’t caused by Bordetella bronchiseptica bacteria alone.
Pertussis (whooping cough) caused by Bordetella pertussis .
Pertussis (whooping cough) caused by Bordetella pertussis.
A vaccine suitable for use in inducing immunity to whooping cough in humans comprises a synergistic combination of the 69kDa antigen of Bordetella pertussis and toxoided lymphocytosis promoting factor of Bordetella pertussis.
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