Both of these miRNAs impact cellular proliferation through the p53-miRNA circuit, and interact with dihydrofolate reductase (DHFR) and thymidylate synthase (TS).

A subset of these miRNAs are regulated in the short term following an ischemic event indicating that these miRNAs play an important role in the induction of subsequent pathological events.

In specific embodiments, this application also discloses mi RNA, mi RNA target genes, and uses thereof to improve plant drought tolerance.

A method for isolating an miRNA of interest from a sample comprising the miRNA of interest comprising providing the capture probe.

More specifically, the disclosure provides microRNA (miRNA) inhibitor molecules that target to different miRNAs for treating different types of ovarian cancers in a subject.

The present invention relates in general to microRNAs (miRNAs).

The exogenous anti -HCV miRNAs induced gene silencing.

It is intended to provide a method whereby an RNAi activity and an miRNA activity can be conveniently evaluated.

This invention discloses novel microRNAs and their precursors, and recombinant DNA constructs including such novel miRNAs, miRNA precursors, miRNA promoters, and miRNA recognition sites corresponding to the miRNAs.

The short oligonucleotides are particularly effective at alleviating miRNA repression in vivo.

miRNAs that regulate human SPARC and methods of use thereof are described.

To aid in the evaluation of candidate miRNAs, we disrupted the Dicer locus in three human colorectal cancer cell lines and examined known and novel miRNAs in these cells.

The oligonucleotides can include therapeutic oligonucleotides, such as siRNA, antisense RNA and miRNA.

Particularly, upregulation of these miRNAs reduces cellular proliferation.

The polynucleotides are miRNAs, miRNA precursors, and associated nucleic acids.