This invention relates to the production of a retroviral vector which is capable of expressing multiple protein translation events from a single polycistronic mRNA, by using internal ribosome entry sites in place of an internal promoter.
They are further divided into viruses with polycistronic mRNA and those with complex transcription.
Polycistronic mRNA is translated into a polyprotein that is subsequently cleaved to form separate proteins.
Requêtes fréquentes français :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
Requêtes fréquentes anglais :1-200, -1k, -2k, -3k, -4k, -5k, -7k, -10k, -20k, -40k, -100k, -200k, -500k, -1000k,
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