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Reactivity of guanine at m5cpg steps in dna: evidence for electronic effects transmitted through the base pairs ... Benzo[a]pyrenediolepoxide (BPDE) and several other aromatic carcinogens form guanine adducts with an identical selectivity for m5CpG, and in certain cancers G to T transversion mutation ‘hotspots’ in the p53 tumor suppressor gene are more frequent at this sequence than at guanines in other sequences....

général - core.ac.uk -

Itgb6 loss of function mutations cause autosomal recessive...p.Ala143Thr) and an ITGB6 transversion mutation in Exon 6 (g.27415T>A...

PDF: hmg.oxfordjournals.org

Four novel germline mutations in the mlh1 and pms2 mismatch repair genes in patients with hereditary nonpolyposis colorectal cancer... The first was a transversion mutation c.346A>C...

PDF: doc.rero.ch