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pempidine

santé / chimie - iate.europa.eu
Thermoregulatory changes induced by cholinomimetic substances introduced into the cerebral ventricles of sheep....4.Atropine given 10 min before injections of carbachol, physostigmine or oxotremorine completely inhibited their hyperthermic effects, but pretreatment with the ganglion-blocking drug, pempidine, caused no inhibition....
santé / vie sociale / droit pénal - core.ac.uk - PDF: www.pubmedcentral.nih.gov
The innervation of the rat cervix and its pharmacology in vitro and in vivo...(1.9 × 10(-7) mol/kg) or pempidine (3.2...

Publications scientifiques

Absorption, metabolism and elimination of pempidine in the ratPempidine (1,2,2,6,6-pentamethylpiperidine) is a ganglion blocking agent introduced recently for the treatment of hypertension by oral administration of its hydrogen tartrate....
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Evaluation of the antagonism of nicotine by mecamylamine and pempidine in the brain... Initial evidence for the existence of central nicotinic receptors was based on the fact that nicotine produced a number of behavioral effects that were antagonized by ganglionic blockers that crossed the blood-brain barrier, such as mecamylamine and pempidine....
général - core.ac.uk - PDF: scholarscompass.vcu.edu
The pharmacological actions of pempidine and its ethyl homologuePempidine, and other highly active ganglion blocking agents of the polyalkylpiperidine series, were developed from tertiary alkylamines, themselves weakly active, on the hypothesis...
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov


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