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Uptake of diphtheria toxin and its fragment a moiety by mammalian cells in culture.... This most likely happens by binding of fragment B to receptors on the membrane and by subsequent toxin-membrane interaction so that ultimately fragment A, the enzymatically active moiety, is transported tothe cell interior....
général - core.ac.uk - PDF: www.pubmedcentral.nih.gov
Endocytosis and intracellular sorting of ricin and shiga toxin ... These toxins consist of one moiety that binds the toxin molecule to cell surface receptors, and another enzymatically active moiety that enters the cytosol after endocytic uptake of the toxin....
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